This product is cylindrical, some have branches, the upper end is thicker, 30 ~ 90cm long, 1 ~ 3.5cm in diameter. The surface is pale brownish yellow or light tan, with irregular longitudinal wrinkles or longitudinal furrows. Hard and tough, not easy to break, section fiber, and show powder, yellow and white leather, light yellow wood, radial texture and cracks...
Chinese pharmacopoeia:Radix Astragali
English name:RADIX ASTRAGALI
This product is the dried root of Astragalus SPP. (Fisch.) Bge. Var. mongholicus (Bge.) Hsiao or Astragalus SPP. (Fisch.) Bge. Spring, autumn two seasons digging, remove fibrous roots and root head, sun dry.
This product is cylindrical, some have branches, the upper end is thicker, 30 ~ 90cm long, 1 ~ 3.5cm in diameter. The surface is pale brownish yellow or light tan, with irregular longitudinal wrinkles or longitudinal furrows. Hard and tough, not easy to break, cross section of strong fiber, and show powder, yellow and white skin, light yellow wood, there are radial texture and cracks, old root center occasionally have decayed, dark brown or empty. The breath is micro, taste is micro sweet, chew of micro have bean fishy taste.
1. Membranous pod astragalus: in the sandy loam area of shrub and dry slope. Distributed in heilongjiang, jilin, liaoning, hebei, shanxi, Inner Mongolia, shaanxi, gansu, ningxia, qinghai, shandong, sichuan and xizang provinces.
2. Inner Mongolia astragalus: born in the mountains. Distributed in heilongjiang, jilin, Inner Mongolia, hebei, shanxi and xizang provinces.
(1) cross section of this product: the cells of the cork are in multiple rows. The inner layer of the plug is 3 ~ 5 rows of thick horn cells. The external rays of phloem are often curved and fissure; Fiber into bundles, wall thickness, wood-like or micro-wood-like, and screen group interactive arrangement; Stone cells are sometimes seen near the inner wall of the thrombus. The cambium forms a ring. Xylem ducts scattered singly or 2 ~ 3 together; There are wood fibers between the vessels; A single or two to four swarms of stone cells are sometimes seen in the rays. Parenchyma cells contain starch granules. Powder yellow and white. The diameter is 8 ~ 30 meters. The walls are thick and there are longitudinal cracks on the surface. The primary wall is often separated from the secondary wall. Tube with margin perforated colorless or orange yellow, with margin perforated tightly arranged. Stone cells are rare, round, oblong or irregular in shape, with thick walls.
(2) the powder amount of this product for 3 g, methanol 20 ml, heating reflux for 1 hour, filtration, the filtrate and the neutral alumina column (100 ~ 120 mesh, 5 g, diameter 10 ~ 15 mm), 100 ml elution with 40% methanol, collect the eluent, dry, residual water 30 ml to dissolve, n-butyl alcohol extract of water saturation 2 times, every time 20 ml, merger of n-butyl alcohol liquid; Wash with water twice, 20ml each time; The water liquid was discarded, the n-butanol liquid was evaporated and dried, and the residue was dissolved by adding 0.5ml methanol as the test solution. Another astragaloside iv control was taken and methanol was added to make a solution containing 1mg per 1ml as the control solution.
According to thin layer chromatography (appendix Ⅵ B) test, each 2 mu l learned these two solution, each point in the same silica G thin layer plate, chloroform - lower methanol-water (13:7:2) solution as an agent, and taken out, dry spray with 10% ethanol solution of sulfuric acid in the 105 ℃ heating to the spot color is clear. In the chromatogram of the test product, the same tan spots were found in the sunlight and the same orange fluorescent spots were found in the ultraviolet lamp (365nm) at the corresponding positions of the chromatogram of the control product.
Take this meal is about 1.5 g [another meal to determine proper moisture at the same time the first method (appendix Ⅸ H)], precision said, soxhlet extractor, and 40 ml of methanol, cold soak overnight, right amount, add methanol circumfluence 4 hours, extract recovery methanol and enriched to dry, residue 10 ml of water, heat to dissolve, the water saturation of n-butyl alcohol extract 3 times, every time 20 ml, combination of n-butyl alcohol extract, ammonia solution was used to extract 2 times, every time 20 ml, abandon to ammonia liquid, n-butyl alcohol liquid zhenggan residue water 3 ~ 5 ml to dissolve, put the cold, Type by D101 macroporous adsorption resin column (diameter 1.5 cm, 12 cm) long, with 50 ml of water elution, abandon to liquid water, reoccupy 30 ml 40% ethanol elution, abandon to 40% ethanol elution liquid, following with 50 ml 70% ethanol elution and collect the eluent, top up, use methanol dissolved and transferred to the 2 ml volumetric flask and add methanol to scale, shake well, as the test solution.
In addition, the astragaloside iv control was precisely weighed, and methanol was added to make a solution containing 1mg per 1ml, which was used as the control solution. According to thin layer chromatography (appendix Ⅵ B) test, precision learn 2 and 6 mu mu l l of test sample solution and reference substance solution 2 and 4 mu mu l l, intersection, respectively, in the same silica G thin layer plate, with chloroform, methanol and water (13:6:2) placed under 10 ℃ lower overnight solution for expansion agent, and taken out, dry spray with 10% ethanol solution of sulfuric acid in the 100 ℃ heating to the spot color is clear, take out, on the thin layer plate cover glass plate of the same size, fixed with tape around according to thin layer chromatography (TLC) (appendix Ⅵ thin-layer scanning method B) scan, wavelength: S =530nm R=700nm s=530nm R=700nm s=530nm R=700nm
This product is calculated as dry product and contains no less than 0.040% astragaloside iv (C41H68O14).
Processing: remove impurities, separate size, wash, moisten, thick slice, dry
Astragalus membranaceus honey: astragalus, as honey method (appendix Ⅱ D) to not glue the hand.
Sexual taste: sweet, warm.
Meridian: to the lung, spleen meridian.
Function and function:
Filling gas solid surface, diuretic tonk, discharge pus, collect ulcer muscle. For deficiency of qi, loose food and stools, depression of middle qi, prolonged diarrhea, prolapse of anus, collapse of blood and stool, spontaneous sweating on the surface, qi deficiency, edema, difficulty in ulceration, chronic ulceration, deficiency of blood, yellow, internal heat and thirst. Chronic nephritis albuminuria, diabetes.
Usage and dosage:9 ~ 30g.
Storage: place ventilated and dry place, moistureproof, moth-proof.